William J Griffiths 
Metabolomics, Metabonomics and Metabolite Profiling 

The completion of gene sequencing has resulted in an intensified investigation of the proteome and metabolome. Metabolite profiling methods used for disease diagnosis have been expanded with the advent of new technology and are being applied extensively in the quest for the discovery of new markers for diseases. In this comprehensive resource, the Editor draws together experts from the field and provides an insightful introduction into the technology and methodology. Metabolomics, Metabonomics And Metabolite Profiling covers a broad range of topics including: * Mass spectrometry and NMR in metabolite profiling * Current applications of metabolite profiling for disease diagnosis * Studies of specific metabolite classes * Plant metabolites * Metabolite data mining * Global systems biology This book is a must have, up-to-date, reference which will appeal to academics, students, technicians and professionals working in, or joining this field.

Table des matières

1. Mass Spectrometry for Metabolite Identification; 2. 1D and 2D NMR Spectroscopy: from Metabolic Fingerprinting to Profiling; 3. Steroids, Sterols and the Nervous System; 4. Phospholipid Profiling; 5. New Developments in Multi-dimensional Mass Spectrometry-Based Shotgun Lipidomics; 6. Neutral Lipidomics and Mass Spectrometry; 7. Bioinformatics of Lipids; 8. Mass Spectrometry in Glycobiology, JoÒo Rodrigues; 9. Matrix Assisted Laser Desorption Ionisation Mass Spectrometric Imaging – Principles and Applications; 10. Plant Metabolomics; 11. Data Mining for Metabolomics; 12. Metabonomics and Global Systems Biology;