Diabetes has reached epidemic proportions, and the cardiovascular
complications of diabetes are life-threatening and disabling. This
book is unique in providing a simple explanation of the biochemical
role of PKC in diabetes complications, which allows clinicians to
understand why PKC inhibitors (in development) are an exciting
prospect for future treatment to slow progression of eye & foot
complications.
New features of this Second Edition include:
* * Updated throughout to reflect the impact of recent major
clinical trials on current clinical practice
* Includes a major new section on diabetic neuropathy
* Revised section on diabetic retinopathy
Each chapter is short and succinct, focusing on 'best
practice’. There are key learning points at the end of each
chapter, with numerous helpful tables, figures and clinical
images.
complications of diabetes are life-threatening and disabling. This
book is unique in providing a simple explanation of the biochemical
role of PKC in diabetes complications, which allows clinicians to
understand why PKC inhibitors (in development) are an exciting
prospect for future treatment to slow progression of eye & foot
complications.
New features of this Second Edition include:
* * Updated throughout to reflect the impact of recent major
clinical trials on current clinical practice
* Includes a major new section on diabetic neuropathy
* Revised section on diabetic retinopathy
Each chapter is short and succinct, focusing on 'best
practice’. There are key learning points at the end of each
chapter, with numerous helpful tables, figures and clinical
images.
€54.99
Spis treści
CONTENTS.List of contributors.
Preface.
SECTION 1. MICRO- AND MACROVASCULAR COMPLICATIONS OF
DIABETES.
Chatper 1. The burden of diabetes complications.
Chapter 2. Risk factors.
Chapter 3. Diabetic nephropathy.
Chapter 4. Coronary heart disease and diabetes.
Chapter 5. Diabetes and cerebrovascular disease.
Chapter 6. Erectile dysfunction.
Chapter 7. Evidence0based interventions to prevent or retard
vascular complications.
SECTION 2. DIABETIC RETINOPATHY AND ASSOCIATED OPHTHALMIC
DISORDERS.
Chapter 8. Diabetic retinpathy: epidemiology and risk
factors.
Chapter 9. Classification and diagnosis of diabetic
retinopathy.
Chapter 10. Pathogenesis of diabetic retinopathy.
Chapter 11. Diabetic maculopathy.
Chapter 12. Proliferative diabetic retinopathy.
Chapter 13. Non-retinal diabetic ocular complications.
Chapter 14. Pictorial case studies.
SECTION 3. DIABETIC NEUROPATHY.
Chapter 15. Diabetic neuropathy: epidemiology and risk
factors.
Chapter 16. Classification and diagnosis of diabetic
neuropathy.
Chapter 17. Pathogenesis of diabetic neuropathy.
Chapter 18. Treatment of diabetic neuropathy.
SECTION 4. PATHOGENESIS OF GLYCAEMIC VASCULAR
DYSFUNCTION.
Chapter 19. Pathophysiological mechanisms.
Chapter 20. Protein kinase C.
Chapter 21. Protein kinase C activation and vascular
permeability.
Chapter 22. Harmful effects of protein kinase C activation in
cardiovascular and renal tissues.
Chapter 23. Therapeutic potential for isoform-selective protein
kinase C inhibitors.
Index
O autorze
Richard Donnelly MD Ph D FRCP FRACP is Professor of Vascular Medicine at the University of Nottingham and Honorary Consultant Physician at the J. O’Neil Diabetic Centre, Derbyshire Royal Infirmary, Derby, UK
Język Angielski ● Format PDF ● Strony 240 ● ISBN 9780470751497 ● Rozmiar pliku 2.4 MB ● Redaktor Richard Donnelly & Edward Horton ● Wydawca John Wiley & Sons ● Opublikowany 2008 ● Ydanie 2 ● Do pobrania 24 miesięcy ● Waluta EUR ● ID 2323759 ● Ochrona przed kopiowaniem Adobe DRM
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