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Overview: Transporters as Targets for Drug Discovery.- Membrane Transporters: Structure, Function and Targets for Drug Design.- Design of Monoamine Reuptake Inhibitors: SSRIs, SNRIs and NRIs.- Atypical Dopamine Uptake Inhibitors that Provide Clues About Cocaine’s Mechanism at the Dopamine Transporter.- The Design, Synthesis and Structure–Activity Relationship of Mixed Serotonin, Norepinephrine and Dopamine Uptake Inhibitors.- Molecular Imaging of Transporters with Positron Emission Tomography.- Pharmacology of Glutamate Transport in the CNS: Substrates and Inhibitors of Excitatory Amino Acid Transporters (EAATs) and the Glutamate/Cystine Exchanger System x c ?.- Glycine Transporters and Their Inhibitors.
Língua Inglês ● Formato PDF ● Páginas 254 ● ISBN 9783540879121 ● Tamanho do arquivo 4.9 MB ● Editor Susan Napier & Matilda Bingham ● Editora Springer Berlin ● Cidade Heidelberg ● País DE ● Publicado 2009 ● Carregável 24 meses ● Moeda EUR ● ID 2164567 ● Proteção contra cópia DRM social
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