Fas Signaling is focused on the signaling mechanisms and biology of the prototypic death receptor Fas, also called CD95 or APO-1. The chapters of this book cover, besides the well recognized apoptosis-related functions of Fas, its emerging role as a proinflammatory cytokine and as an inducer of alternative forms of cell death. Fas Signaling aims to provide the reader with an up-to-date survey of the various aspects of Fas biology and the open questions of the field are addressed. This title is intended for Ph.D and post-doctoral students starting to work in the field, but is also useful for everyone with an interest in the biology of this exciting molecule.
€149.79
Зміст
Fas L and Fas.- Fas L-Independent Activation of Fas.- Role of Ceramide in CD95 Signaling.- Regulation of Fas Signaling by FLIP Proteins.- Fas-Induced Necrosis.- Fas—More Than an Apoptosis Inducer.- Retrograde Fas Ligand Signaling.- Fas L and Fas in Liver Homeostasis and Hepatic Injuries.- Fas-Activation, Development and Homeostasis of T Cells.- The Fas L-Fas System in Disease and Therapy.- Tools for Activation and Neutralization of Fas Signaling.
Мова Англійська ● Формат PDF ● Сторінки 160 ● ISBN 9780387345734 ● Розмір файлу 11.7 MB ● Редактор Harald Wajant ● Видавець Springer US ● Місто NY ● Країна US ● Опубліковано 2007 ● Завантажувані 24 місяців ● Валюта EUR ● Посвідчення особи 2144896 ● Захист від копіювання Соціальний DRM
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