Leon V. Berhardt 
Advances in Medicine and Biology. Volume 188 

This edited manuscript includes six chapters, each describing recent advancements in medicine and biology. Chapter One investigates the impact on psychopathology of adding lurasidone to clozapine for people with treatment-resistant schizophrenia. Chapter Two reviews some intestinal protozoa and their diseases in immunodeficient patients. Chapter Three addresses the general role of inflammasomes and reviews current knowledge of potential therapeutic application of inflammasomes in neurological disorders. Chapter Four looks at the role of ion channel activation and downstream signal transduction in modulating Sertoli cell behavior to a final physiological response and its potential impact on spermatogenesis. Chapter Five includes a comprehensive view on sulfur-containing saponins and their mode of actions. Lastly, Chapter Six assesses the pathophysiological impacts of Spironucleus salmonis infection on the seawater adaptability of juvenile chum salmon.