Lowell T. Duncan 
Advances in Health and Disease. Volume 15 

Advances in Health and Disease. Volume 15 explores the current knowledge relating extracellular calreticulin to human pathologies, focusing on cancer, rheumatoid arthritis, systemic lupus erythematosus, wound repair and the retroviral infection with human T-cell lymphotropic virus type 1. Following this, the authors provide an overview of the tumor markers and scoring systems as well as it’s utilization for effective diagnosis of female adnexal masses. Appropriate discrimination between benign and malignant mass results in the correct choice between conservative and surgical management. This collection also presents the way in which two B-glucans play a vital role in innate immunity modulation, and are therefore predicted to be candidates for alternative therapies against inflammatory diseases. Subsequently, the authors present indications, techniques, complications and treatment regarding the use of polyacrylamide for facial wasting rehabilitation. Medical literature shows how facial wasting is recognized as a stigma of the infection for the patient-self, and as such facial features restoring is crucial to the social life of HIV positive patients. In conclusion, the major issues regard reduced nostril aperture and nasal fossae volume, and degree of sinus pneumatization are presented. Endoscopic sinus surgery and its main use in pediatric patients is described, as well as the advantages of this less invasive surgery.