Lowell T. Duncan 
Advances in Health and Disease. Volume 42 

This edited volume includes seven chapters, each of which details a recent scientific advancement in health and disease. Chapter One describes polycystic ovary syndrome (PCOS) and elaborates various treatment, therapeutic, and management strategies for PCOS which may help in relieving its economic and social burden. Chapter Two addresses the ethical problems of the use of human fetal cell cultures in the manufacture of vaccines as well as other ethical dilemmas associated with vaccines. Chapter Three reviews fundamental aspects of imaging in the diagnosis of pneumomediastinum, including the normal mediastinal anatomy and relevant variants in plain radiography and computed tomography. Chapter Four summarizes current literature involving fasted exercise and health benefits and discusses the proposed mechanisms, aiming to determine fasted aerobic exercise applicability as a health-promoting strategy. Chapter Five examines the role that aerobic exercise plays in osteoporosis prevention and management, and how different exercise modalities contribute to bone health. Chapter Six reviews the main features of spontaneous pneumomediastinum, both in its asymptomatic and emergent forms, with focus on clinical signs and symptoms, natural course and the differential diagnosis. Lastly, Chapter Seven covers the current strategies for the management of gestational diabetes mellitus.